Antibiotic Resistance

Objectives: Clinical guidelines or guidance is an important tool for preventing and treating antimicrobial-resistant (AMR) infections. We sought to understand and support the effective use of guidelines and guidance for AMR infections.

The National Action Plan for Combating Antibiotic-Resistant Bacteria 2015 – 2020 (2015 Plan) has guided the U.S. Government’s response to combating antibiotic-resistant infections since its establishment in 2015. The U.S. Government’s Interagency Task Force for Combating Antibiotic-Resistant Bacteria (CARB) has produced four previous reports on progress toward the 2015 Plan.

COVID-19 has impacted antimicrobial drug prescribing both directly, through COVID-19 treatment, and indirectly, through the reduced spread of illnesses for which antimicrobial drugs are commonly prescribed.

The National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB), 2020-2025, presents coordinated, strategic actions that the United States Government will take in the next five years to improve the health and wellbeing of all Americans by changing the course of antibiotic resistance. This Plan is based on the U.S.

Antibiotic Resistance continues to pose a significant threat to our Nation’s public health. To coordinate and enhance the public health response to this threat, the U.S. Government developed the National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB). The CARB Task Force is co-chaired by HHS, USDA, and DOD.