Biomedical Research, Science, & Technology

The cost of bringing a medical product to the U.S. market has been increasing and clinical trials constitute a large portion of these costs. In drug development, the clinical phase lasts an average of around 95 months compared to 31 months for the non-clinical phase and accounts for 69 percent of overall R&D costs (DiMasi, et al., 2016).

This series of five case studies describe evidence-based, innovative, and exemplary practices that support positive mental health for children. The case studies in five organizations highlight key elements of prevention and promotion efforts in early childhood mental health, as well as the contextual factors that support implementation.Available Reports:

Efforts to promote positive mental health and prevent the onset of mental health difficulties are crucial for supporting healthy early childhood social-emotional development and well-being.

This landing page presents the abstract of a paper published in Health Affairs. The full text of the article is available at: https://www.healthaffairs.org/doi/abs/10.1377/hlthaff.2023.00837.

The evolution of pathogens to resist the drugs used to treat infections is an ongoing threat to public health, animal health, food production, and national security. Globally, a recent analysis estimated that 1.2 million deaths were caused by antibiotic-resistant (AR) bacteria in 2019, making this threat a leading cause of death for people of all ages worldwide.

In October 2022, ASPE convened a virtual technical expert panel (TEP) to discuss policy options that encourage interstate licensure among behavioral health providers.

Assisted outpatient treatment (AOT) is a civil court procedure whereby a judge orders an adult with serious mental illness (SMI) to comply with community-based treatment. Developed as a less restrictive alternative to involuntary hospitalization, AOT focuses on individuals at risk of clinical deterioration or rehospitalization because they do not voluntarily comply with prescribed treatment.

This environmental scan, conducted by Mathematica and funded by ASPE, examines the types of direct and direct costs to patients associated with clinical trial participation. It also explores the effect of COVID-19 on costs to patients, including cost implications of clinical trial innovations widely implemented during COVID-19 and other efforts to increase diversity of clinical trials.

In 2023, ASPE launched a research project to understand the impacts of COVID-19 on the clinical trial enterprise and identify key lessons learned.

Medical product shortages are an ongoing public health concern, with at least 140 products in shortage as of July 2024.We use the Household Pulse Survey to examine how many adults are affected by shortages of critical medical products in the United States.In fall 2023, shortages of medical products impacted about 38.8 million (18 percent) of individuals in the United Stat